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– 좌석 : 100석 – 사용 가능 장비 : Cisco화상장비, 음향시설, 빔프로젝트, 리어스크린, 냉난방시설, 정수기 – 사용 가능 시간 : 오전 : 9시 ~ 12시 / 오후 : 1시 ~ 7시

Polygenic architecture of brain structure and function, behaviors, and psychopathologies in children

Abstract Childhood brain development involves dynamic remodeling shaped by genetic influences contributing to long-term neurodevelopmental variation. Here we report integrative analyses of over 8600 children, using 7 brain imaging-derived phenotype (IDP) modalities, polygenic scores (PGS) of 33 complex traits, and 266 cognitive and psychological phenotypes. Most brain IDPs show low-to-moderate SNP-based heritability, lower than typically […]

Attractor dynamics of working memory explain a concurrent evolution of stimulus-specific and decision-consistent biases in visual estimation

Highlights Delayed estimates are biased in stimulus-specific and decision-consistent ways Behavioral and neural growth of stimulus-specific bias implies drift to attractors Decisions steer stimulus-specific memory drift, augmenting decision-consistent bias Task-optimized RNNs reveal mechanisms for such decision-steered attractor dynamics   Summary Sensory evidence tends to be fleeting, often unavailable when we categorize or estimate world features. […]

Canonical cortico-hippocampal dynamics underlie memory of navigational episodes and its early decline in aging

Abstract Successful encoding of a navigational episode entails the dynamic processing of perceptual information, time-locked to the appearance of salient landmarks and turns along the way. We hypothesized that identical navigational experiences will be represented in a similar manner across individuals and that a deviation from such canonical dynamics in the cortico-hippocampal network may underlie […]

Long-term physical exercise facilitates putative glymphatic and meningeal lymphatic vessel flow in humans

Abstract Regular voluntary exercise has been shown to increase waste transport through the glymphatic system in mice. Here, we investigate the impact of physical exercise on both upstream and downstream brain waste clearance in healthy volunteers via noninvasive MR imaging. Putative glymphatic influx, evaluated using intravenous contrast-enhanced dynamic T1 mapping, increases significantly at the putamen […]