공지사항
[2025] 제1회 SNUBIC Art Fair Series 워크샵
작성자
admbic
작성일
2025-08-12
조회
30
주최: 서울대학교 뇌영상센터(SNUBIC)
과제명: 인프라 고도화: 고경사 확산 자기공명 영상장치 도입을 통한 뇌 구조와 기능에 대한 난제 해결(RS-2024-00435727)
후원: 국가연구시설장비진흥센터(NFEC), 교육부
후원: 국가연구시설장비진흥센터(NFEC), 교육부
행사명: SNUBIC ART FAIR SERIES #1
일시: 2025.07.24(목요일) 10:30AM~
장소: 서울대학교 28동 303호
*접수방법: QR코드, 7월 21일 오후 12시까지 사전접수
*접수방법: QR코드, 7월 21일 오후 12시까지 사전접수
연사: 이종호 교수(서울대학교 공과대학 전기전자공학부)
발표 제목: Advanced diffusion and myelin imaging
Abstract:
In this talk, I will introduce and explain several advanced neuroimaging techniques that go beyond conventional diffusion tensor imaging (DTI) to offer deeper insights into brain microstructure. Specifically, I will cover three widely used diffusion MRI methods—Neurite Orientation Dispersion and Density Imaging (NODDI), Diffusion Kurtosis Imaging (DKI), and Diffusion Spectrum Imaging (DSI)—as well as a myelin imaging technique based on magnetic susceptibility source separation, also known as χ-separation.
NODDI provides a model-based framework for estimating neurite density and orientation dispersion, making it useful for assessing both gray and white matter integrity. DKI quantifies the non-Gaussian behavior of water diffusion, enabling sensitive detection of microstructural complexity and tissue heterogeneity. DSI, a model-free technique, reconstructs the full diffusion propagator in q-space, allowing it to resolve complex fiber configurations such as crossing and kissing fibers with high angular resolution.
In addition to these diffusion-based methods, I will present χ-separation, a novel technique that disentangles magnetic susceptibility sources—primarily iron and myelin—by leveraging their distinct biophysical contributions to the MR signal. This method enables quantitative and source-specific mapping of myelin, providing complementary information to diffusion metrics in understanding brain structure and pathology.
By comparing the principles, strengths, and applications of these techniques, this talk aims to highlight their synergistic roles in advancing both basic neuroscience and clinical neuroimaging.
- 간단 소개: 고급 확산영상 기법(NODDI, DKI, DSI)과 자기민감도 소스 분리를 활용한 마이엘린 이미징(χ-separation) 등, 기존 DTI를 넘어서는 뇌 미세구조를 정밀 평가하는 첨단기법들을 소개하고 장비 도입 배경과 연구 적용 가능성에 대해 논의합니다.
